Filipe Dezordi

I'm

About

I'm interested in science, evolution, virology, workflows, and the development of bioinformatics tools. I have a degree in Biotechnology but my expertise is in Bioinformatics. Currently, I'm a Ph.D. Candidate on Sciences at Fundação Oswaldo Cruz (FioCruz), bioinformatician volunteer at Rede Genômica FioCruz (RGF - Fiocruz Genomic Network) and work as Bioinformatician Analyst at Hospital Israelita Albert Einstein (HIAE), Brazil.


Bioinformatician

My work on HIAE involves the development and application of bioinformatics workflows to analyze human genomics and code development to automatize tasks on AWS and through the use of APIs. To do it, I mainly develop with Workflow Development Language (WDL), Amazon Web Services (AWS), Docker, Git, Shell Script and Python in agile teams following the Scrum methodology.

During my Ph.D., I worked with genomic surveillance of SARS-CoV-2. I built the ViralFlow - with other members of RGF - a workflow that performs a set of viral genomic analyses from sequencing raw data. Moreover, I published key studies to understand several aspects of SARS-CoV-2 evolution during the pandemic in Brazil as well as I collaborated with several studies mainly on the biology of mosquito vectors of arbovirus and paleovirology.

To perform my Ph.D. research I worked with Multi-user Linux servers, PBS queue system, Docker, Singularity, Python, R and Shell Script.

  • Github: https://github.com/dezordi
  • City: Recife, Brazil
  • Age: 29
  • Degree: Master


In my free time, I like to create and share content related to bioinformatics on Linkedin and Instagram, read books, draw and last but not least, I like to have a good time with my family and friends.

Numbers and Skills

Some figures about my academic production and skills as Bioinformatician.

Citations

Papers Published

Examination Boards

Books read

NGS Data Analysis 90%
Python 85%
Shell Script 75%
R 60%
Workflow Development Language (WDL) 60%
Rust 5%
Phylogenetic-core analysis90%
Linux Utilities (Awk, Sed, Grep, etc) 80%
Docker/Singularity 75%
Git/Github 75%
Amazon Web Services (AWS) 70%
HTML+CSS 20%

Resume

A briefy story of my way.

Sumary

Filipe Dezordi

Bioinformatician Analyst with 4+ years of experience, developing and applyng bioinformatics tools and workflow to study viral and human genomics.

  • Recife, Pernambuco, Brazil.
  • filipe.zimmer@fiocruz.br

Education

PhD Candidate in Biosciences and Biotechnology on Health

2020 - Present

Fundação Oswaldo Cruz (FioCruz) - IAM, PE

My Ph.D. project research was about SARS-CoV-2 genomics and evolution. During this period, I did my research on the Bioinformatics Core of FioCruz and became a member of Rede Genomica FioCruz (FioCruz Genomic Network). I worked on a multi-user cluster with PBS system, I improved my skills in Python and Shell Script programming, as well as learned R, Docker, and Singularity. I developed - with the RGS staff - the ViralFlow, the workflow that was used to analyze more than 38k genomes in Brazil during the SARS-CoV-2 pandemic.

Master Degree in Biosciences and Biotechnology on Health

2018 - 2020

Fundação Oswaldo Cruz (FioCruz) - IAM, PE

My master's degree research was about Endogenous Viruses Elements in mosquito genomes. During this period, I did my research on the Entomology Department and Bioinformatics Core of FioCruz. I worked on multi-user Linux servers and started programming in Python and Shell Script.

Bachelor of Biotechnology

2013 - 2017

Universidade Federal do Pampa, São Gabriel, RS

During this period I started in the research field working for 3 years as a volunteer at Proteomics Applied Lab, where I studied Transposable Elements in a parasitoid wasp draft genome, using Galaxy and GUI software.

Professional Experience

Full Bioinformatician Analyst

2024 - Present

Genesis Genomics, Brazil, Remote

My current position, in April 2024 the departament in which I worked at the Hospital Israelita Albert Einstein went through a merger process with another company, creating the Genesis Genomics, to which I was transferred to continue working in the same position

  • Automations and Integrations staff.
  • Daily development of codes using Python.
  • Development and update of python CLI tools / packages.
  • Development of serverless systems using AWS CDK in python.
  • CI/CD with github actions and AWS code pipelines.

Full Bioinformatician Analyst

2022 - 2024

Hospital Israelita Albert Einstein (HIAE - Varsomics), Recife, PE

  • Routines of bioinformatics analysis applied to precision medicine.
  • Daily development of codes using Python and WDL.
  • Worked on codes automatize tasks on AWS, and to include new features on Human genomics workflows.
  • Integrate the BioDevOps team, building AWS infraestructure using AWS CDK (IaC).
  • On september 2023 change to full remote position.
  • On April 2024 transferred to Genesis Genomics.

Volunteer Bioinformatician

2020 - Present

Rede Genomica FioCruz (RGF), Recife, PE

  • Workflow development.
  • SARS-CoV-2 genomic data analysis, foccused on intrahost variants and large phylogenies.
  • R plots to reports and scientific papers.

Publications

My papers as principal or collaborator author published in Scientific Journals.

  • All
  • 2018
  • 2020
  • 2021
  • 2022
  • 2023
  • 2024

Drosophila parasitoid wasps bears a distinct DNA transposon profile

Contribuitions: Bioinformatics analysis, Data curation and plots.

HTT-DB: new features and updates

Contribuitions: Manual data curation.

De novo Assembly and Annotation of the Antarctic Alga Prasiola crispa Transcriptome

Contribuitions: Preliminary data analysis.

In and outs of Chuviridae endogenous viral elements: origin of a potentially new retrovirus and signature of ancient and ongoing arms race in mosquito genomes

Contribuitions: Experimental design, all bioinformatics analysis (except molecular modeling), pictures design.

Multiple introductions followed by ongoing community spread of SARS-CoV-2 at one of the largest metropolitan areas in the Northeast of Brazil

Contribuitions: Writing in house scripts for datasets treatments, karyoploter analysis, phylogeny by maximum likelihood analysis, spike mutation analysis.

Systematic Review of Wolbachia Symbiont Detection in Mosquitoes: An Entangled Topic about Methodological Power and True Symbiosis

Contribuitions: Secondary data review; data analysis; figures design.

Lying in wait: the resurgence of dengue virus after the Zika epidemic in Brazil

Contribuitions: DENV1 genomes curation to submission; DENV1 genomes submission to NCBI; Epidemiological data collection and data treatment.

Metatranscriptomic analysis identifies different viral-like sequences in two neotropical Mansoniini mosquito species

Contribuitions: Mosquito collection, data analysis, EVEs filter.

COVID-19 in Amazonas, Brazil, was driven by the persistence of endemic lineages and P.1 emergence

Contribuitions: Intrahost variant analysis.

The ongoing evolution of variants of concern and interest of SARS-CoV-2 in Brazil revealed by convergent indels in the amino (N)-terminal domain of the Spike protein

Contribuitions: Genomic data analysis.

Identification of a Novel SARS-CoV-2 P.1 Sub-Lineage in Brazil Provides New Insights About the Mechanisms of Emergence of Variants of Concern.

Contribuitions: Genomic data analysis.

Emergence and Spread of the SARS-CoV-2 Variant of Concern Delta across Different Brazilian Regions

Contribuitions: Genomic data analysis.

ViralFlow: an automated workflow for SARS-CoV-2 genome assembly, lineage assignment, mutations and intrahost variants detection

Contribuitions: Conceptualisation, workflow development, methodology, formal analysis.

Unusual SARS-CoV-2 intra-host diversity reveals lineages superinfection

Contribuitions: Conceptualisation, methodology, formal analysis.

Phylogenetic-based inference reveals distinct transmission dynamics of SARS-CoV-2 lineages Gamma and P.2 in Brazil

Contribuitions: Genomic data analysis.

Real-life evaluation of a rapid antigen test (DPP® SARS-CoV-2 Antigen) for COVID-19 diagnosis of primary healthcare patients, in the context of the Omicron-dominant wave in Brazil

Contribuitions: Phylogenetic analysis.

SARS-CoV-2 intra-host diversity, antibody response, and disease severity after reinfection by the variant of concern Gamma in Brazil

Contribuitions: Intrahost analysis.

Ancient origin of Jingchuvirales derived glycoproteins integrated in arthropod genomes

Contribuitions: Conceptualisation; Analysis Design; formal data analysis.

RNA virome of sylvatic mosquitoes from northeast Brazil reveals a divergent and diverse insect-specific viral community

Contribuitions: Mosquito sampling, Supported the sequencing data.

Assessment of clinical characteristics and viral load in individuals infected by Delta and Omicron variants of SARS-CoV-2

Contribuitions: Genomic data analysis.

Highly pathogenic avian influenza H5N1 virus infections in pinnipeds and seabirds in Uruguay: implications for bird-mammal transmission in South America

Contribuitions: Data analyis, Microreact dashboard construction.

Spatiotemporal transmission of SARS-CoV-2 lineages during 2020–2021 in Pernambuco—Brazil

Contribuitions: Conceptualisation, genomic data analysis, phylogenetic and phylodinamycs analysis.

ViralFlow v1.0—a computational workflow for streamlining viral genomic surveillance

Contribuitions: Conceptualisation, software development, tests, docummentation.

Highly divergent and diverse viral community infecting sylvatic mosquitoes from Northeast Brazil

Contribuitions: Samples collection, support on data analysis.

Infection of South American coatis (Nasua nasua) with highly pathogenic avian influenza H5N1 virus displaying mammalian adaptive mutations

Contribuitions: Data analysis.

EEfinder, a general purpose tool for identification of bacterial and viral endogenized elements in eukaryotic genomes

Contribuitions: Conceptualisation, software development, tests.

Codding

Repositories for tools, scripts or websites that I`ve developed and that are available publicly.

Extracurricular

Activities outside work and academia.



Blog Posts




Text and News




Talks & Podcasts